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16 In 2019, two groups independently reported that the FSP1 (ferroptosis suppressor protein 1)-CoQ 10 (coenzyme Q 10 )-NAD(P)H pathway inhibits ferroptosis via a GPX4-independent mechanism

Hft et al., 2014)

IDO activity commonly leads to the suppression of the immune system [126]

We prioritized peer reviewed studies that provided mechanistic evidence and clear relevance to osteoarthritis cartilage repair, and excluded non peer reviewed reports or studies lacking mechanistic characterization